While it is simple to use the Foldscope, extensive development, prototyping, and design for manufacturing went into producing the tool. The design leverages recent advances in micro-optics as well as the concept of "flat manufacturing" for large-scale production. To learn more, please read details in open-access Foldscope paper.
Cybulski JS, Clements J, Prakash M (2014) Foldscope: Origami-Based Paper Microscope. PLoS ONE 9(6): e98781. doi: 10.1371/journal.pone.0098781